AltTox.org

Non-animal Methods for Toxicity Testing

Other Literature/Websites


Last Updated: December 22, 2008
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Additional sources of information on scientific and policy issues relevant to the development and use of non-animal test methods.


Alternatives Websites

3R Research Foundation Bulletin and News

ACuteTox: EC funded project for developing in vitro methods to predict human acute toxicity

AltTox.org

Altweb

ARTEMIS: EC funded project for developing an in vitro 3D neural tissue-like model that can mimick memory acquisition/learning for use in pharmacology and toxicology applications

BBMO (Biosensors Based on Molecular Organization): EC funded project for developing in vitro methods based on biosensor technology for drug screening and environmental control protocols

BioSim: 6th Framework Programme of EC; network of researchers using simulation techniques to improve drug development and reduce animal use

Johns Hopkins Center for Alternatives to Animal Testing (CAAT)

carcinoGENOMICS: EC funded project for developing in vitro methods to assess the carcinogenic potential of compounds

COMICS: EC funded project for developing in vitro Comet assay and cell arrays for screening chemicals for potential genotoxic and cytotoxic effects

Dr Hadwen Trust Science Room

European Centre for the Validation of Alternative Methods (ECVAM)

ECVAM Database Service on Alternative Methods to Animal Experimentation

European Consensus Platform for Alternatives (ECOPA)

European Society of Toxicology In Vitro (ESTIV)

Fund for the Replacement of Animals in Medical Experiments (FRAME)

Go3R: New Internet search engine for locating information on replacement, reduction, and refinement alternative methods

Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)

Institute for In Vitro Sciences, Inc. (IIVS)

In Vitro Testing Industrial Platform (IVTIP)

INVITROHEART: EC funded project for developing stable human cardiomyocyte cell lines and in vitro human models for pharmaceutical and toxicology testing

Liintop: EC funded project for developing in vitro liver and intestine models for pharmacokinetic and pharmacodynamic studies

National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs)

Netherlands Centre for Alternatives to Animal Use (NCA)

NHR DEVTOX: EC funded project for conducting a prospective analysis of the role and mechanisms of nuclear hormone receptors in developmental and reproductive biology and determining their potential for this application

PREDICTOMICS: EC funded project for developing a novel testing platform for chronic liver and kidney toxicity that will reduce animal testing

ReProTect: EC funded project for developing an integrated set of tests for assessing reproductive/ developmental toxicity

Sens-it-iv: EC funded project for developing in vitro methods to assess potential lung or skin sensitizers

TOXDROP: EC funded project for developing "nanodrop" cell microarrays for high content toxicity screening

Tracking System for Alternative test methods Review, Validation and Approval in the context of EU Regulations on Chemicals (TSAR): Joint Research Center of the European Commission website for tracking the validation status of alternative methods

University of California Center for Animal Alternatives

VITROCELLOMICS: EC funded project for developing stable cell lines and in vitro human liver models for preclinical drug testing by the pharmaceutical industry

Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments (ZEBET), Federal Institute for Risk Assessment (BfR), Germany

Centre for Alternative and Complementary Methods to Animal Testing (ZET), Austria


Scientific Websites/Glossaries

ADMETnews.net: news and application resource for laboratory scientists utilizing ADME-Toxicology

Allen Brain Atlas Neuroscience Gateway: resource for research, news, and events in neuroscience and genomics

Cold Spring Harbor Laboratory Press: Online access to scientific books, journals, laboratory manuals, protocols, and symposia

DevTox: resource for researchers in developmental toxicology; includes harmonized nomenclature and a database of images

European Science Foundation (ESF)

Glossary of Biotechnology Terms

Intute: Science, Engineering and Technology: internet resources covering the physical sciences, engineering, computing, geography, mathematics and environmental science

National Academy of Sciences

Regenerationnet: internet portal for information on regenerative biology

Science/AAAS

Stem Cell Research News


Government Websites/ Information

Chemicals Policy Initiative: An organization formed to advance policy debate on reforming chemicals policy in the United States; their website contains information and resources on US Federal and state chemicals policy, as well as chemicals policy in Canada, Latin America, Europe, Africa, and Asia-Pacific regions

Community Research & Development Information Service (CORDIS): European research & development and innovation activities

EDQM's Alternatives to Animal Testing Conference Proceedings (April 23-24, 2008)

European Commission Booklet on FP6 and FP7 projects concerned with alternative testing

Federal Register

Legislative Information: from the Library of Congress

MedlinePlus: Medical Encyclopedia

US National Institutes of Health (NIH)

NIH Stem Cell Information

National Institute of Environmental Health Sciences

National Science Foundation

Risk Assessment Information System: risk assessment information and tools

Science.gov: science information provided by U.S. government agencies


Technical Reports

5th World Congress Abstracts

6th World Congress Abstracts

BioCompare Technical Articles database

CAAT Technical Reports

Environmental Risk Assessment and Management (ERASM)

FoodRisk.org: information on chemical hazards risk assessment

MEIC Program: databases and information on in vitro tests to predict systemic toxicity

NAS report, Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

NAS report, Toxicity Testing in the Twenty-first Century: A Vision and a Strategy

RAinfo: online source for worldwide regulatory affairs information

Safety Assessment of Cosmetics in Europe (book)

Skin Care Forum

Stem Cells in Predictive Toxicology: 35-page report based on workshop held July 2008 by the California Institute for Regenerative Medicine (CIRM), the California agency devoted to stem cell research


Other Informational Websites

Google Scholar

The British Library

US Library of Congress

US National Library of Medicine

Wikipedia: encyclopedia of user generated information - needs to be verified

WWW Virtual Library


Patent Searches

European Patent Office

FreePatentsOnline

Google Patent Search

Stem Cell Patents

United States Patent and Trademark Office Electronic Business Center


Newsletters/ E-mail Alerts

Alan Brain Atlas Neuroscience Gateway

Altweb Newsletter

DB-ALM Newsletter

ECVAM Monthly Newsletters

EurActiv.com e-mail updates: European news and policy issues

FDA, Regulatory Research Perspectives

Nature Omics Gateway e-mail alerts

NCA Newsletter

NC3Rs e-newsletter

NIEHS, Environmental Factor

NLM-Tox-Enviro-Health-L: email announcement list to broadcast updates on resources, services, and outreach in toxicology and environmental health

NTP News Updates

P&G Forward Focus newsletter

ScienceInfo Grant E-Newsletter: US and Europe editions - free subscription