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Non-animal Methods for Toxicity Testing

Genotoxicity: References


Last Updated: December 6, 2007
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Combes, R., Grindon, C., Cronin, M.T., et al. (2007). Proposed integrated decision-tree testing strategies for mutagenicity and carcinogenicity in relation to the EU REACH legislation. Altern. Lab. Anim. 35, 267-287.

ECVAM. (2002). Genotoxicity and carcinogenicity. Altern. Lab. Anim. 30, Suppl. 1, 83-93.

Maurici, D., Aardema, M., Corvi, R., et al. (2005). Genotoxicity and mutagenicity. Altern. Lab. Anim. 33, Suppl. 1, 117-130.

Tice, R.R., Agurell, E., Anderson, D., et al. (2000). The single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing. Environ. Mol. Mutagen. 35, 206-221.

United Nations Economic Commission for Europe (UNECE). (2004). Globally Harmonized System of classification and labeling of chemicals (GHS). Part 3. Health and environmental hazards. Chapter 3.5. Germ cell mutagenicity. Available here.

Yu, T.W. & Dashwood, R.H. (2007). Measuring antigenotoxic effects using the Ames test and Comet assay. Am. Biotech. Lab. 25, 22-23.