AltTox.org

Non-animal Methods for Toxicity Testing

In the Spotlight
Meetings & Events
Get Involved

References: Honegger, Monnet-Tschudi & Zurich


Last Updated: February 2, 2009
Print |
Email
  1. Honegger, P. & Richelson, E. (1977). Biochemical differentiation of aggregating cell cultures of different fetal rat brain regions. Brain Res. 133, 329-339.
  2. Honegger, P., Lenoir, D. & Favrod, P. (1979). Growth and differentiation of aggregating fetal brain cells in a serum-free defined medium. Nature. 282, 305-308.
  3. Honegger, P. & Lenoir, D. (1982). Nerve growth factor (NGF) stimulation of cholinergic telencephalic neurons in aggregating cell culture. Devl. Brain Res. 3, 229-238.
  4. Lenoir, D. & Honegger, P. (1983). Insulin-like growth factor I (IGF I) stimulates DNA synthesis in fetal rat brain cell cultures. Devl. Brain Res. 7, 205-213.
  5. Zurich, M.-G., Monnet-Tschudi, F. & Honegger, P. (1994). Long-term treatment of aggregating brain cell cultures with low concentrations of lead acetate. Neurotoxicology. 15, 715-720.
  6. Monnet-Tschudi, F., Zurich, M.-G., Pithon, E., van Melle, G. & Honegger, P. (1995). Microglial responsiveness as a sensitive marker for trimethyltin (TMT) neurotoxicity. Brain Res. 690, 8-14.
  7. Sorg, O., Schilter, B., Honegger, P. & Monnet-Tschudi, F. (1998). Increased vulnerability of neurones and glial cells to low concentrations of methylmercury in a prooxidant situation. Acta Neuropathol. 96, 621-627.
  8. Zurich, M.-G., Monnet-Tschudi, F., Bérode, M. & Honegger, P. (1998). Lead acetate toxicity in vitro: dependence of the cell composition of the cultures. Toxicol. In Vitro. 12, 191-196.
  9. Eskes, C., Juillerat-Jeanneret, L., Leuba, G., Honegger, P. & Monnet-Tschudi, F. (2003). Involvement of microglia-neuron interactions in the TNF-a release, microglial activation and neurodegeneration induced by trimethyltin. J. Neurosci. Res. 71, 583-590.
  10. Honegger, P. & Matthieu, J.-M. (1996). Selective toxicity of the general anesthetic propofol for GABAergic neurons in rat brain cell cultures. J. Neurosci. Res. 45, 631-636.
  11. Honegger, P., Pardo, B. & Monnet-Tschudi, F. (1998). Muscimol-induced death of GABAergic neurons in rat brain aggregating cell cultures. Devl. Brain Res. 105, 219-225.
  12. Pardo, B. & Honegger, P. (1999). High sensitivity of immature GABAergic neurons to blockers of voltage-gated calcium channels. Devl. Brain. Res. 115, 9-16.
  13. Monnet-Tschudi, F., Hazenkamp, A., Perret, N., Zurich, M.-G., Mangin, P., Giroud, C. & Honegger, P. (2008). Delta-9-tetrahydrocannabinol accumulation, metabolism and cell-type-specific adverse effects in aggregating brain cell cultures. Toxicol. Appl. Pharmacol. 228, 8-16.
  14. Pouly, S., Storch, M.K., Matthieu, J.-M., Lassmann, H., Monnet-Tschudi, F. & Honegger, P. (1997). Demyelination induced by protein kinase C-activating tumor promoters in aggregating brain cell cultures. J. Neurosci. Res. 49, 121-132.
  15. Zurich, M.-G., Honegger, P., Schilter, B., Costa, L.G. & Monnet-Tschudi, F. (2004). Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos. Toxicol. Appl. Pharmacol. 201, 97-104.
  16. Monnet-Tschudi, F., Zurich, M.-G., Sorg, O., Matthieu, J.-M., Honegger, P. & Schilter, B. (1999). The naturally occurring food mycotoxin fumonisin B1 impairs myelin formation in aggregating brain cell culture. Neurotoxicology. 20, 41-48.
  17. Zurich, M.-G., Lengacher, S., Braissant, O., Monnet-Tschudi, F., Pellerin, L. & Honegger, P. (2005). Unusual atrocyte reactivity caused by the food mycotoxin ochratoxin A in aggregating rat brain cell cultures. Neuroscience. 134, 771-782.
  18. Braissant, O., Honegger, P., Loup, M., Iwase, K., Takiguchi, M. & Bachmann, C. (1999). Hyperammonemia : regulation of argininosuccinate synthetase and argininosuccinate lyase genes in aggregating cell cultures of fetal rat brain. Neurosci. Lett. 266, 89-92.
  19. Braissant, O., Cagnon, L., Monnet-Tschudi, F., Speer, O., Wallimann, T., Honegger, P. & Henry, H. (2008). Ammonium exposure alters the CNS gene regulation for creatine transport and synthesis. Eur. J. Neurosci. 27, 1673-1685.
  20. Cagnon, L. & Braissant, O. (2009). CNTF protects oligodendrocytes from ammonia toxicity: intracellular signaling pathways involved. Neurobiol. Disease. 33, 133–142.
  21. Monnet-Tschudi, F., Zurich, M.-G. & Honegger, P. (1993). Evaluation of the toxicity of different metal compounds in the developing brain using aggregating cell cultures as a model. Toxicol. In Vitro. 7, 335-339.
  22. Monnet-Tschudi, F., Zurich, M.-G., Riederer, B.M. & Honegger, P. (1995). Effects of trimethyltin (TMT) on glial and neuronal cells in aggregate cultures: dependence on the developmental stage. Neurotoxicology. 16, 97-104.
  23. Monnet-Tschudi, F., Zurich, M.-G. & Honegger, P. (1996). Comparison of the developmental effects of two mercury compounds on glial cells and neurons in aggregate cultures of rat telencephalon. Brain Res. 741, 52-59.
  24. Eskes, C., Honegger, P., Jones-Lepp, T., Varner, K., Matthieu, J.-M. & Monnet-Tschudi, F. (1999). Neurotoxicity of dibutyltin in aggregating brain cell cultures. Toxicol. In Vitro. 13, 555-560.
  25. Zurich, M.-G., Honegger, P., Schilter, B., Costa, L.G. & Monnet-Tschudi, F. (2000). Use of aggregating brain cell cultures to study developmental effects of organophosphorus insecticides. Neurotoxicology. 21, 599-606.
  26. Monnet-Tschudi, F., Zurich, M.-G., Schilter, B., Costa, L.G. & Honegger, P. (2000). Maturation-dependent effects of chlorpyrifos and parathion and their oxygen analogs on acetylcholinesterase and neuronal and glial markers in aggregating brain cell cultures. Toxicol. Appl. Pharmacol. 165, 175-183.
  27. Zurich, M.-G., Eskes, C., Honegger, P., Bérode, M. & Monnet-Tschudi, F. (2002). Maturation-dependent neurotoxicity of lead acetate in vitro: implication of glial reactions. J. Neurosci. Res. 70, 108-116.
  28. Monnet-Tschudi, F., Zurich, M.-G. & Honegger, P. (2007). Neurotoxicant-induced inflammatory response in three-dimensional brain cell cultures. Hum. Exp. Toxicol. 26, 339-346.
  29. Preynat-Seauve, O., Suter, D., Tirefort, D., Turchi, L., Virolle, T., Chneiweiss, H., Foti, M., Lobrinus, J.-A., Stoppini, L., Feki, A., Dubois-Dauphin, M. & Krause, K.H. (2009). Development of human nervous tissue upon differentiation of embryonic stem cells in three-dimensional culture. Stem Cells. 2008 Dec 11 [Epub ahead of print].