Blaauboer, B.J., Forsby, A., Houston, J.B., et al. (2000). An integrated approach to the prediction of systemic toxicity by using biokinetic models and biological in vitro test methods. In M. Balls, A.-M. van Zeller & M. Halder (Eds.), Progress in the reduction, refinement and replacement of animal experimentation. (pp. 525-536). Amsterdam: Elsevier.
ECVAM. (2002a). Target organ and target system toxicity. Altern. Lab. Anim. 30, Suppl. 1, 71-82.
ECVAM. (2002b). Biokinetics. Altern. Lab. Anim. 30, Suppl. 1, 55-70.
Li, A.P. (2004). In vitro approaches to evaluate ADMET drug properties. Curr. Top. Med. Chem. 4, 701-706.
Li, A.P. (2007). Human hepatocytes: isolation, cryopreservation and applications in drug development. Chem. Biol. Interact. 168, 16-29.
Li, A.P. (in press). In vitro evaluation of human xenobiotic toxicity: Scientific concepts and the novel Integrated Discrete Multiple Cell Co-Culture (IdMOC) Technology. ALTEX (in press).
Li, A.P. (in press). Human hepatocytes as an effective alternative experimental system for the evaluation of human drug properties: General concepts and assay procedures. ALTEX (in press).
Li, A.P., Bode, C. & Sakai, Y. (2004). A novel in vitro system, the integrated discrete multiple organ cell culture (IdMOC) system, for the evaluation of human drug toxicity: comparative cytotoxicity of tamoxifen towards normal human cells from five major organs and MCF-7 adenocarcinoma breast cancer cells. Chem. Biol. Interact. 150, 129-136.
Pfaller, W., Balls, M., Clothier, R., et al. (2001). Novel advanced in vitro methods for long-term toxicity testing. ECVAM Workshop Report 45. Altern. Lab. Anim. 29, 393-426.
Prieto, P., Clemedson, C., Meneguz, A., et al. (2005). Subacute and subchronic toxicity. Altern. Lab. Anim. 33, Suppl.1, 109-116.
Prieto, P., Baird, A.W., Blaauboer, B.J., et al. (2006). The assessment of repeated dose toxicity in vitro: a proposed approach. The report and recommendations of ECVAM workshop 56. Altern. Lab. Anim. 34, 315-341.
Spielmann, H., Bochkov, N.P., Costa, L., et al. (1998). 13th meeting of the scientific group on methodologies for the safety evaluation of chemicals (SGOMSEC): alternative testing methodologies for organ toxicity. Environ. Health Perspect. 106, Suppl. 2, 427-439.
United Nations Economic Commission for Europe (UNECE). 2004. Globally Harmonized System of classification and labeling of chemicals (GHS). Part 3, Health and environmental hazards. Chapter 3.9. Specific target organ systemic toxicity - repeated dose. Available at: http://www.unece.org/trans/danger/publi/ghs/ghs_rev00/00files_e.html
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