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Non-animal Methods for Toxicity Testing

Author Biography: Corsini

Last Updated: May 27, 2011
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Emanuela Corsini is currently Associate Professor of Toxicology at the School of Pharmacy at the Università degli Studi di Milano in Milan, Italy. She got her PhD in Food and Environmental Toxicology in 1993 at the Università degli Studi di Milano. She is currently head of the Laboratory of Immunotoxicology and Immunopharmacology, which is part of the Laboratories of Toxicology directed by Professor C.L. Galli.

Dr. Corsini’s research program encompasses three distinct areas of immunotoxicology. At present, the primary focus of her laboratory centers on the refinement of alternative in vitro tests to identify and discriminate contact allergens from irritants and respiratory sensitizers, based on the use of DC-like cells and keratinocytes, and to classify allergens according to their potency. The other area of research centers on the understanding at the molecular level the mechanism of action of immunotoxic/immunomodulatory compounds (i.e. perfluorinated compounds, pesticides, vegetal extracts) on innate and adaptive immunity. Finally, immunosenescece represents the other area of interest of her laboratory. Specifically, studies are being conducted to define the role of RACK-1 and protein kinase C in the decline or remodeling of the immune responses associated with aging, and to identify compounds able to reverse such changes (i.e. DHEA, natural extracts). She is author of more than 100 publications in peer reviewed journals and 20 book chapters.

She is active in numerous scientific and professional organizations, serves on several editorial boards of toxicology and in vitro journals. She is member of the Italian Society of Toxicology, and of the American Society of Toxicology. From 1999-2005 she served as Treasurer of the Association for in vitro Toxicology; from 2009 she is Member of EUROTOX Education Sub Committee, from 2005 she is the Chair of the Immunotoxicology and Chemical Specialty Section at EUROTOX, and from 2010 she is a Member of the IUTOX Executive Committee.

She is the recipient of several awards and honors, including Award for the best paper published in Fundamental and Applied Toxicology (21: 71-81, 1993); Outstanding Young Investigator Award from the Immunotoxicology Specialty Section of the SOT (2004); Recipient of the EUROTOX/P&G "Animal Alternatives Award 2008".


Prof. Emanuela Corsini
Laboratory of Toxicology
Department of Pharmacological Sciences
University of Milan
Via Balzaretti 9,
20133 Milan, Italy
E-mail: emanuela.corsini@unimi.it