Responsibility for implementing and/or enforcing laws established by Congress rests with federal civil servants in a number of regulatory and research agencies. Many of the agencies with influence on the use of animals and/or alternatives in regulatory toxicology are located within the US Department of Health and Human Services, while others operate independently. In addition, two key interagency bodies have been established to coordinate programs and activities of mutual interest.
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
Agency for Toxic Substances and Disease Registry (ATSDR)
National Institute of Occupational Safety and Health (NIOSH)
Food and Drug Administration (FDA)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Environmental Health Sciences (NIEHS)
Independent Agencies
Consumer Product Safety Commission (CPSC)
Department of Agriculture (USDA)
Department of Defense (DoD)
Department of Transportation (DOT)
Environmental Protection Agency (EPA)
Occupational Safety and Health Administration (OSHA)
Interagency Bodies
National Toxicology Program (NTP)
NTP Interagency Center for the Evaluation of Alternative Toxicological Methods - Interagency Coordinating Committee on the Validation of Alternative Methods (NICEATM-ICCVAM)
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Chemicals
Cosmetics
Endocrine disruptors
Food additives & flavorings
Genetically modified foods
Human biologics
Nanoscale particles
Nutritional supplements
Pesticides
Pharmaceuticals
Veterinary biologics
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